The purpose of this study is to evaluate the Immunogenicity and safety of the simultaneously vaccination of Inactivated Enterovirus 71 Vaccine (EV71) and seasonal influenza vaccine(SIV)
Main subjects: The seroconversion rate for each antigen when EV71 is administrated with SIV Secondary subjects: The positive rate of antibody for each antigen when EV71 is administrated with SIV The safety for each antigen when EV71 is administrated with SIV
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
1,134
Give 2 doses of EV71 +SIV, get 2 blood samples before the first dose and 28-43 days after the last dose.
Give 2 doses of EV71 , get 2 blood samples before the first dose and 28-43 days after the last
Give 2 doses of SIV , get 2 blood samples before the first dose and 28-43 days after the last
Liandu Center for Disease Control and Prevention
Lishui, Zhejiang, China
immunogenicity evaluation
The positive rate of antibody
Time frame: change from baseline antibody concentration at 28 days after the last dose
safety evaluation: The occurrence of adverse events
The occurrence of adverse events
Time frame: up to 30 days after every injection
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.