This clinical RCT study intends to combined different forms of multi-channel tDCS with the routine cognitive training process to treat patients with post-stroke cognitive dysfunction. The therapeutic effects among single-channel tDCS group, multi-channel tDCS and pseudo-multichannel tDCS group will be compared. Brain magnetic resonance mechanism research will also be included to reveal the possible mechanism of multi-channel tDCS technology for PSCI brain network. Thus, the efficacy and mechanism of multi-channel tDCS in post-stroke cognitive function rehabilitation will be researched both in the clinical and basic levels.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
180
multi-channel transcranial direct current stimulation, tDCS
single-channel transcranial direct current stimulation
Rainbowfish Rehabilitation Nursing Care
Hangzhou, Zhejiang, China
RECRUITINGSAHZhejiangU
Hangzhou, Zhejiang, China
RECRUITINGZhejiang Provincial People's Hospital
Hangzhou, Zhejiang, China
RECRUITINGSouthwest Hospital
Chongqing, China
RECRUITINGMMSE
Mini-mental State Examination
Time frame: Change from Baseline MMSE at 2 weeks and 3 months after intervention
MoCA
Montreal Cognitive Assessment
Time frame: Change from Baseline MoCA at 2 weeks and 3 months after intervention
AVLT
The Auditory-Verbal Learning Test
Time frame: Change from Baseline AVLT at 2 weeks and 3 months after intervention
WAIS-DST
WAIS Digit Symbol Test
Time frame: Change from Baseline WAIS-DST at 2 weeks and 3 months after intervention
DEX
Dysexecutive Ques-tionnaire
Time frame: Change from Baseline DEX at 2 weeks and 3 months after intervention
GNAT
Go/No-go Association Task
Time frame: Change from Baseline GNAT at 2 weeks and 3 months after intervention
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