Intraoperative Phenylephrine Infusion to Reduce Postoperative Shivering in Lower Segment Caesarean Section

Universiti Kebangsaan Malaysia Medical Centre118 enrolled

Overview

Assessment of whether and how phenylephrine infusion reduces postoperative shivering in spinal anaesthesia.

This study aims to evaluate whether phenylephrine infusion can reduce postoperative shivering among patients scheduled for elective lower segment caesarean section under spinal anaesthesia.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

118

Conditions

Postoperative Shivering

Interventions

PhenylephrineDRUG

Phenylephrine infusion 0.3ml/kg/hour (equivalent to 0.5mcg/kg/min, phenylephrine dilution is 100mcg/ml in 20ml syringe)

Normal salineDRUG

Normal saline infusion 0.3ml/kg/hour (normal saline in 20ml syringe)

Eligibility

Sex: FEMALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * More than 18 years of age * American Society of Anesthesiologists (ASA) II patients * Patients with singleton pregnancy who are scheduled to undergo elective lower segment caesarean section under spinal anaesthesia Exclusion Criteria: * Patients with contraindication to phenylephrine * Patients with evidence of fever or infection, or hypothermia preoperatively * BMI ≥ 40 * Height \<150cm

Locations (1)

Pusat Perubatan Universiti Kebangsaan Malaysia

Kuala Lumpur, Malaysia

Outcomes

Primary Outcomes

Presence and intensity of shivering

Any presence of shivering intraoperatively is recorded. The intensity of shivering is recorded based on the Bedside Shivering Assessment Scale (BSAS) with a scoring of 0-3 (0 = no shivering, 1 = shivering localised to neck and/or thorax, 2 = shivering involves gross movement of upper extremities, 3 = shivering involves gross movements of the trunk, upper and lower extremities).

Time frame: 2 hours

Secondary Outcomes

Change in patient's core and skin temperature

Patient's core (tympanic membrane) and skin (forehead) temperature is measured using an infrared thermometer.

Time frame: 2 hours

Data from ClinicalTrials.gov

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