A Prospective Study on The"Management of Hypertension in Young and Middle-aged Subjects in Enterprises Setting"

Yan Li2,000 enrolled

Overview

In recent years, with the investment from government in the health management of the elderly, community management of hypertension in the elderly has made great progress in management rate and standardized management, but the management of young and middle-aged patients with hypertension is still blank. Workplace pressure measurement may be more suitable for most of the young and middle-aged patients to find high blood pressure and monitor blood pressure changes in time. However, there is not much research on workplace pressure measurement. Whether blood pressure measurement in the workplace can reduce the white coat effect, and how it relates to home blood pressure and ambulatory blood pressure is still unclear.

Study Type

OBSERVATIONAL

Enrollment

2,000

Conditions

Hypertension Blood Pressure

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Male and female sex, aged 18-65 years 2. Three different daytime workplace blood pressure measurements meet the limits: systolic blood pressure ≥ 120 mmHg, or diastolic blood pressure ≥80 mmHg 3. Hypertensive patients who are taking antihypertensive drugs 4. Willing to provide information about disease history and lifestyle 5. Willing to receive follow-up for up to 2-3 years 6. Sign the informed consent Exclusion Criteria: 1. Having the onset of cardiovascular and cerebrovascular diseases such as stroke, myocardial infarction or heart failure within 6 months 2. Having a history of atrial fibrillation or frequent arrhythmia 3. Complicating other diseases that are not suitable for the trial, such as thyroid disease with active medication, acute infectious diseases, chronic mental illness, and tumors 4. The subject is participating in other clinical studies.

Outcomes

Primary Outcomes

Diagnostic classification in hypertension

Differences in diagnostic classification between workplace blood pressure and daytime ambulatory blood pressure in the classification of hypertension (masked hypertension or white coat hypertension)

Time frame: 2 years

Secondary Outcomes

Change in different blood pressure measurement

Differences in workplace blood pressure, daytime ambulatory blood pressure, home blood pressure and 24-hour ambulatory blood pressure

Time frame: 2 years

The distribution of heart rate in young and middle-aged subjects

The distribution of heart rate in young and middle-aged subjects who were diagnosed with hypertension

Time frame: 2 years

Progression of target organ damage

Differences in the progression of target organ damage between controlled or uncontrolled subjects or between subjects with fast and slow heart rate

Time frame: 2 years

The development of with-coat hypertension

The development of white-coat hypertension as persistent hypertension and other types of hypertension or normal blood pressure and changes in target organ damage

Time frame: 2 years

The proportion of masked hypertension in patients with normal high blood pressure

The proportion of masked hypertension in patients with normal high blood pressure and the change in outcome after treatment intervention and changes in target organ damage

Time frame: 2 years

A Prospective Study on The"Management of Hypertension in Young and Middle-aged Subjects in Enterprises Setting"

Overview

Conditions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Secondary Outcomes