MultiOrgan Multi-Parametric MRI Study

Perspectum43 enrolled

Overview

To determine the reproducibility of a single quantitative multiparametric MRI for the assessment of body composition and multiple organ structures.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Type 2 Diabetes

Interventions

Multiparametric MRIOTHER

A standardised MRI protocol that provides a number of quantitative metrics on liver and other organs relevant to type 2 Diabetes - pancreas, kidneys, spleen, heart, lungs and aorta

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Any person over 18 years of age. * Participant is willing and able to give informed consent for participation in the investigation. * EITHER: Participant has Type 2 Diabetes OR: Person is a healthy volunteer Exclusion Criteria: * The participant may not enter the investigation if they have any contraindication to magnetic resonance imaging (incl. pregnancy, extensive tattoos, pacemaker, shrapnel injury, severe claustrophobia). * Any other cause, including a significant disease or disorder which, in the opinion of the investigator, may either put the participant at risk because of participation in the investigation, or may influence the result of the investigation, or the participant's ability to participate in the investigation

Locations (3)

Beaver House

Oxford, United Kingdom

Oxford Centre for Magnetic Resonance

Oxford, United Kingdom

Gemini One

Oxford, United Kingdom

Outcomes

Primary Outcomes

Assessment of repeatability (precision under the same conditions in the same subjects: 2 separate MRI acquisitions on the same scanner) of body composition and multiple organ metrics.

To determine the repeatability of multiparametric MRI in the assessment of body composition and multiple organ structures obtained within a single MR scanning session (liver, pancreas, aorta, heart, kidney, lungs and spleen)

Time frame: 24 months

Secondary Outcomes

Assessment of the reproducibility (precision under different measurement conditions: same participants scanned on separate MRI scanners at both 1.5T and 3T) of multiparametric MRI for the assessment of body composition and multiple organ metrics.

To determine the reproducibility of multiparametric MRI in the assessment of body composition and multiple organ structures (liver, pancreas, aorta, heart, kidney, lungs and spleen) obtained within separate MR scanning sessions.

Time frame: 24 months

Data from ClinicalTrials.gov

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