The purpose of this study is to evaluate testicular function measured as testosterone level and semen quality.
Men having undergone surgery for testicular torsion between 01.01.2003 - 12.31.2012 will receive a invitation to participate in this study. It is expected that 110 patients can be identified and about 65% of them will participate. These men will undergo a andrological evaluation, deliver a semen sample, have a blood sample taken and undergo a testicular ultrasound. Control group: Men attending the fertility counseling at Herlev hospital will be offered participation in this study. The fertility counseling demands that men who contact the clinic have never had their sperm analyzed, have not tried to get pregnant with their partner for more than a year and that they have no prior knowledge of their fertility. Primary endpoint: * Semen quality measured as sperm concentration * Total testosterone level Secondary endpoint: Semen parameters * Semen volume (ml) * Sperm concentration (x 106/ml) * Sperm motility (%) (både klasse AB og ABC) * sperm morphology * IgA-bound spermatozoa (%) * IgG-bound spermatozoa (%) Hormones * FSH * LH * PRL * Testosterone * Estradiol * Inhibin B * Insulin-like peptide 3 * SHBG Data points: * Paternity * Time to pregnancy * Partner (yes/no) * Any fertility treatment? * Pain? (VAS score) * Symptoms of testesterone deficiency symptoms * Andrological evaluation * Testicular ultrasound * Testicular torsion events in the family * Date of surgery * Date of follow up meeting * Surgery details
Study Type
OBSERVATIONAL
Enrollment
140
Department of Growth and Reproduction
Copenhagen, Denmark
RECRUITINGSperm concentration
Amount of motile sperm cells (\* 10\^6)
Time frame: 8-17 years after surgical intervention
Testosterone level
ng/ml
Time frame: 8-17 years after surgical intervention
Semen parameters as an indicator of overall testicular exocrine function
Compared with results from control group
Time frame: 8-17 years after surgical intervention
Hormone level as an indicator of testicular endocrine function
Follicle stimulating hormone, luteinizing hormone, prolactin, testosterone, estradiol, inhibin B, sex hormone-binding globulin, albumin
Time frame: 8-17 years after surgical intervention
MAR test result correlated to the type of surgery
MAR test of sperm cells
Time frame: 8-17 years after surgical intervention
Difference in sperm morphology and motility correlated to the type of surgery and compared to control group
Morphology and motility (%)
Time frame: 8-17 years after surgical intervention
Paternity as a measure of fertility
Number of kids if any.
Time frame: 8-17 years after surgical intervention
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