Transcranial direct current stimulation (tDCS) combined with computerized cognitive addiction therapy(CCAT) for methamphetamine(MA) dependent patients in voluntary drug rehabilitation center. Electronic medical systems were applied for drug related knowledge education, self-evaluation and outpatient follow-up reminder after intervention in order to reduce relapse behaviors.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
100
Ture 1-2 mA current of tDCS intervention in patients' binary brain DLPFC areas(20 mm).
Sham tDCS intervention in patients' binary brain DLPFC areas(20 mm).
Shanghai Mental Health Center
Shanghai, China
RECRUITINGChange from Baseline cue-induced craving at 2 weeks
Participants were instructed to watch methamphetamine-related videos by VR and rate their level of craving after smelling and recalling the last time they engaged in drug use. Craving was assessed by visual analog scales (VAS), with 0 mm being "no craving"and 100 mm representing "most craving ever experienced for methamphetamine".
Time frame: 2 weeks
Change from Baseline cue-induced craving at 4 weeks
Participants were instructed to watch methamphetamine-related videos by VR and rate their level of craving after smelling and recalling the last time they engaged in drug use. Craving was assessed by visual analog scales (VAS), with 0 mm being "no craving"and 100 mm representing "most craving ever experienced for methamphetamine".
Time frame: 4 weeks
Attention bias towards methamphetamine
A Chinese version of the MA addiction dot probe task (DPT) is used to evaluate the attention bias towards drugs.
Time frame: 2 weeks，4 weeks
cognitive function
Chinese version of the CogState Battery was used to assess cognitive function.
Time frame: 2 weeks，4 weeks
response inhibition function
stop signal task
Time frame: 2 weeks，4 weeks
reward-related function
Delay Discounting Task
Time frame: 2 weeks，4 weeks
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