Diagnostic Accuracy of the Vegetative and Minimally Conscious State

Hangzhou Normal University150 enrolled

Overview

The aim of this study was to investigate diagnostic accuracy of the vegetative and minimally conscious state: Clinical consensus versus standardized neurobehavioral assessment

In this study, DOC patients with clinical consensus of DOC were enrolled. The investigators used Coma Recovery Scale-revision (CRS-R) to assess consciousness levels for all DOC patients during ten days.

Study Type

OBSERVATIONAL

Enrollment

150

Conditions

Disorder of Consciousness Minimally Conscious State

Interventions

Coma Recovery Scale-revisionDIAGNOSTIC_TEST

Patients were assessed by Coma Recovery Scale-revision to detect the DOC patients enrolled by clinicians.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion 1. at least 18 years old; 2. acquired brain injury; 3. no neuromuscular blockers or sedatives were used within 48 hours of enrollment. Exclusion Criteria: 1. there are functional disorders caused by progressive mental diseases; 2. persistent seizures; 3. unstable vital signs; 4. double upper limb frustration, fracture.

Locations (1)

International Vegetative State and Consciousness Science Institute, Hangzhou Normal University

Hangzhou, Zhejiang, China

Outcomes

Primary Outcomes

Assessed by the Coma Recovery Scale-Revised

All patients were assessed by the Coma Recovery Scale-Revised within 10 days to detect the consciousness level. CRS-R consists of six sub-scales with 23 items, which evaluate the patients' auditory, visual, motor, Oromotor/Verbal, communication and arousal functions. For each subscale, the lower score reflected reflexivity related to the brain stem, while the higher score reflected non-reflexivity related to higher cortical functions (0-23).

Time frame: Within 10 days

Data from ClinicalTrials.gov

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