Safety and Effectiveness of Disposable Pulmonary Surgical Markers in the Localization of Pulmonary Nodules

Inclusion Criteria: * Age 18-70 years old； * Pulmonary nodule, which satisfying any of the following Criteria: * solid nodules with diameter ≤1 cm or solid component ≤1 cm non-purely ground glass, and the distance between the solid component of the nodule and the visceral pleural\>0.5cm; * Pure ground glass opacity (pGGO)； * Before VATS operation, the doctor judge that the nodule is difficult to locate during the operation. * Pulmonary wedge resection or Segmental pulmonary resection under VATS is proposed; * Preoperative evaluation shows that placing marker through bronchus is feasible； * The subject is able to fully understand the requirements of clinical research; * Subject or the legal representative signs the informed consent form. Exclusion Criteria: * Contraindications for bronchoscopy; * Systemic factors: sepsis, history of repeated pulmonary infections, and any type of severe infectious disease within one month of screening； * Severe cardio and pulmonary disease； * Coagulation dysfunction, with a clear tendency to bleed; * General anesthesia contraindication; * Allergic history of nickel-titanium materials; * Breast-feeding or may be or plan to be pregnant during the trial; * Participating in clinical trials of other drugs or medical devices; * Other conditions that Investigator consider the subject to be inappropriate.