Diagnosis of Laryngeal Lesions Using the Probe-based Confocal Laser Endomicroscopy

Inclusion Criteria: 1. 18≤Male or female age ≤85 years old; 2. patients with vocal cord lesions founded by white light laryngoscope and needed to perform laryngeal microsurgery; 3. Willing and able to comply with study procedures and provide written informed consent to participate in the study. Exclusion Criteria: 1. Male or female \<18 years old, or Male or female \>85 years; 2. The patient has abnormal blood or coagulation function, and there is a risk of bleeding during the examination; 3. The patient has severe cardiopulmonary function or liver and kidney dysfunction and cannot tolerate surgery. 4. The patient has a history of allergies to drugs or food. 5. The patient has a positive serotonin sodium allergy test and is allergic to sodium fluorescein; 6. Lactation or pregnant women. 7. Refusal to sign the informed consent form. 8. Others who do not take this test.