This study mainly observed the ischemic index and vascular leakage index changes on ultra-wide field fluorescence angiography after anti-VEGF treatment , and whether these changes correlated with treatment efficacy in patients with macular edema secondary to retinal vein occlusion.
Ultra-wide field fluorescence angiography can clearly observe the peripheral retina. This study mainly observes the ischemic index and vascular leakage index changes on UWFA after anti-VEGF treatment and evaluates these changes associated with treatment efficacy in patients with macular edema secondary to retinal vein occlusion.
Study Type
OBSERVATIONAL
Enrollment
60
Intravitreal injection of Ranibizumab 0.5 MG/0.05 ML
Ultra-wide-field Fluorescein Angiography can clearly observe the peripheral retina
Renmin Hospital of Wuhan University
Wuhan, Hubei, China
RECRUITINGChange in vascular leakage index in different retinal area
Change in vascular leakage index in different retinal area from baseline to 1,2,3,4,6,9 and 12 months
Time frame: Baseline and 1,2,3,4,6,9 and 12 months
Change in non-perfused areas in different retinal area
Change in non-perfused areas in different retinal area from baseline to 1,2,3,4,6,9 and 12 months
Time frame: Baseline and 1,2,3,4,6,9 and 12 months
Change in best corrected visual acuity
Change in best corrected visual acuity from baseline to 1,2,3,4,6,9 and 12 months
Time frame: Baseline and 1,2,3,4,6,9 and 12 months
Change in central macular thickness
Change in central macular thickness from baseline to1,2,3,4,6,9 and12 months
Time frame: Baseline and 1,2,3,4,6,9 and 12 months
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