This study aims to estimate the effect of the practice of a short-term partial fasting compared to a usual alimentation on nausea and vomiting within 5 days after the start of a chemotherapy session on 2 successive chemotherapy courses (4 sessions of chemotherapy) in patients starting treatment with highly emetogenic chemotherapy (ABVD or AVD protocol).
Patients in fasting arm will practice partial fasting during 3 days (D-1, D1 (D day of chemotherapy) and D2) following a food guide during 4 chemotherapy sessions. Patients in usual alimentation arm will continue to take food as usual practice. In each arm, patients will be interviewed at each chemotherapy sessions about nausea and vomiting (number and intensity of nausea and vomiting, treatments taken). Denutrition, quality of life improvement, compliance to partial fasting, treatment response will be evaluate too.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
30
fasting limited to daily 250 kcal during 3 days (day before chemotherapy, the D day of the chemotherapy and the day after chemotherapy)
CHU de la Réunion
Saint-Pierre, France
RECRUITINGnausea and vomiting evaluation and quantification
Anti-emetic tool from MASCC (Multinational Association of Supportive Care in Cancer)
Time frame: Day 1 (first day of the chemotherapy cycle),
nausea and vomiting evaluation and quantification
Anti-emetic tool from MASCC (Multinational Association of Supportive Care in Cancer)
Time frame: day 2 of the chemotherapy cycle
nausea and vomiting evaluation and quantification
Anti-emetic tool from MASCC (Multinational Association of Supportive Care in Cancer)
Time frame: day 3 of the chemotherapy cycle
nausea and vomiting evaluation and quantification
Anti-emetic tool from MASCC (Multinational Association of Supportive Care in Cancer)
Time frame: day 4 of the chemotherapy cycle
nausea and vomiting evaluation and quantification
Anti-emetic tool from MASCC (Multinational Association of Supportive Care in Cancer)
Time frame: day 5 of the chemotherapy cycle
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