Noradrenaline Infusion Versus Phenylephrine Infusion in Improving Serum Lactate Level in HIPEC

Suez Canal University30 enrolled

Overview

ABG PARAMETERS ARE CHANGED DURING HIPEC, WE TRIED TO FIND COMPARISON BETWEEN NORADRENALINE AND PHENYLEPHRINE IN OPTIMIZING ABG PARAMETERS THAT REFLECTS ORGAN PERFUSIONS ESPECIALLY SERUM LACTATE

Arterial blood gas testing is considered one of the most important and widely used test in the detection of acidosis, alkalosis, electrolytes disturbance and tissue perfusion. in regard to tissue perfusion serum lactate above 4 mmol/L indicates poor tissue perfusion. serum lactate could be measured at ABG or separately. in this study we will test the effect of both noradrenaline and phenylephrine on lactate level at ABG during the stage of HIPAC in managing abdominal cancer patients.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

Interventions

NORADRENALINDRUG

DRUG THAT IS IMPROVING TISSUE AND ORGAN PERFUSION

PHENYLEPHRINEDRUG

DRUG THAT IS IMPROVING TISSUE AND ORGAN PERFUSION

Eligibility

Sex: ALLMin age: 35 Years

Medical Language ↔ Plain English

Inclusion Criteria: * CANCER PATIENTS ENROLLED FOR HIPEC Exclusion Criteria: * DRUG SENSITIVITY

Locations (1)

Suez Canal University

Ismailia, Egypt

Outcomes

Primary Outcomes

SERUM LACTATE IN ABG

LANDMARK FOR TISSUE AND ORGAN PERFUSION

Time frame: IMMEDIATELY POSTOPERATIVELY

Data from ClinicalTrials.gov

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