This study is looking to see how a 6-month low carbohydrate diet can affect the body's ability to use energy in addition to the affects it has on the heart and blood vessel health.
Weight gain often occurs following a liver transplant. This weight gain is problematic as it leads to many other health problems. The reasons of this weight gain are still poorly understood. To better understand weight gain, this study is looking to see how a 6-month low carbohydrate diet can affect the body's ability to use energy in addition to the affects it has on heart and blood vessel health. This study will help researchers to better understand weight gain after a transplant. This knowledge will help doctors prevent weight gain after a liver transplant and therefore improve the health of liver transplant patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
42
Initial Weight Loss consultation 1.5 hour session on how to do implement healthy diet and then have a 2-week follow-up class. Information on how to maintain a healthy combination protein, fat and vegetables daily will be provided provided. 4 lifestyle coaching sessions Monthly visits for behavioral and dietary coaching as well as medication management.
Initial Weight Loss consultation 1.5 hour session on how to do implement healthy diet and then have a 2-week follow-up class. Information on how to maintain a LCD will be provided provided. 4 lifestyle coaching sessions Monthly visits for behavioral and dietary coaching as well as medication management.
Virginia Commonwealth University
Richmond, Virginia, United States
Change in weight
Weight will be measured on a standardized scale in kilograms that will be zeroed out prior to the measurement
Time frame: baseline to 6 months
Change in metabolic flexibility
This will be measured in whole room calorimeter and reported as respiratory quotient
Time frame: baseline to 6 months
Change in LDL-C
LDL-cholesterol will be measured using a fasting blood draw and a standard lipid panel.
Time frame: baseline to 6 months
Change in total cholesterol
Total cholesterol will be measured using a fasting blood draw and a standard lipid panel.
Time frame: baseline to 6 months
Change in small dense low-density lipoprotein
Small dense LDL will be measured using a fasting blood draw and a standard lipid panel.
Time frame: baseline to 6 months
Change in adiposity
This will be measured on body composition MRI where subcutaneous and visceral fat will be quantified. Subcutaneous fat and visceral fat volume will measured on body composition MRI in liters (L) and standardized to body height and will be reported as liter/m2
Time frame: baseline to 6 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.