The aim is to assess the efficacy of a mix of Pumpkin Seed Extract, Soy Germ Isoflavonoids and Cranberry (Novex®) in the management of mild to moderate LUTS in BPH patients. The patients will be evaluated based on the severity of LUTS, urological quality of life, and erectile function.
This is a single-arm prospective open-label trial investigating a combination of pumpkin seed, isoflavonoid and cranberry mix in improving LUTS, urological quality of life, and erectile function in BPH patients. The compound will be administered orally two tablets daily for 3 months. Recruited patients will be seen at 3 visits: initial visit (visit 1), 1-month visit (visit 2) and 3-month visit (visit 3) and their data will be collected in a dedicated case report form.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
163
Novex® made of Pumpkin Seed Extract 550mg, Soy Germ Isoflavonoids 50 mg and Cranberry 50mg. The dose is 2 tablets/day taken orally.
Elie El Helou
Beirut, Lebanon
IPSS
Change in IPSS
Time frame: At 1 and 3 months visits
IPSS subscores
Change in IPSS subscores (voiding, filling, nocturia)
Time frame: At 1 and 3 months visits
uQoL
Change in uQoL
Time frame: At 1 and 3 months visits
IIEF-5
Change in IIEF-5
Time frame: At 1 and 3 months visits
Rate of ejaculatory dysfunction and orthostatic hypotension
Rate
Time frame: At 1 and 3 months visits
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.