In view of the current problem of treating high myopic macular schisis, the main purpose of our study is to find out the most appropriate time of surgical intervention, to compare the effectiveness and safety of various surgical methods in the treatment of high myopic macular schisis, and to find out the advantages and disadvantages of each surgical method in the treatment of MF. As well as the outcomes and complications of long-term follow-up.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
400
pars plana vitrectomy+/-cataract
pars plana vitrectomy+/-cataract+gas tamponade
pars plana vitrectomy+internal limiting membrane peeling+/-cataract+/-gas tamponade
Shanghai Aier Eye Hospital
Shanghai, Shanghai Municipality, China
RECRUITINGfoveal thickness
measured by OCT
Time frame: change from baseline foveal thickness at 3, 6, 9, 12 months
retinal thickness of the most significant schisis
measured by OCT
Time frame: change from baseline at 3, 6, 9, 12 months
best corrected visual acuity
BCVA
Time frame: change from baseline at 3, 6, 9, 12 months
mf-ERG
multifocal-ERG
Time frame: change from baseline at 3, 6, 9, 12 months
Visual quality questionnaire
Visual quality questionnaire
Time frame: change from baseline at 3, 6, 9, 12 months
axial length
axial length measured by IOL Master
Time frame: change from baseline at 3, 6, 9, 12 months
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pars plana vitrectomy+internal limiting membrane peeling+/-cataract+/-silicone oil tamponade
posterior scleral reinforcement
posterior scleral reinforcement+pars plana vitrectomy+internal limiting membrane peeling+/-cataract+/-silicone oil tamponade (or gas)
gas tamponade alone