Effects of Abdominal Nerve Block on Postoperative Recovery in Patients Undergoing Gastrointestinal Surgery

Yi Liu200 enrolled

Overview

To explore the effect of general anesthesia combined with transversus abdominis plane block (TAPB) and/or rectus sheath block (RSB) on the recovery of patients with gastrointestinal tumor after surgical treatment.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

200

Conditions

Colon Cancer Rectal Cancer Gastric Cancer

Interventions

Group Abdominal Nerve Block with local anestheticsOTHER

surgical under general anesthesia combined with transversus abdominis plane block (TAPB) and/or rectus sheath block (RSB) with 0.2% ropivacaine

Group Abdominal Nerve Block with salineOTHER

surgical under general anesthesia combined with transversus abdominis plane block (TAPB) and/or rectus sheath block (RSB) with not 0.2% ropivacaine but 0.9% saline.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Aged 18 to 80 years. 2. ASA 1-3. 3. Clinical diagnosis of gastric carcinoma and colorectal cancer without metastasis. 4. Surgery for gastrointestinal surgery. Exclusion Criteria: 1. Patients and their family members refuse to accept the clinical trial; 2. Complicated with acute cholangitis, gastrointestinal bleeding or ascites, etc.; 3. Hepatic encephalopathy, psychosis or neuropathy; 4. Body weight for acid-base and electrolyte imbalances, endotoxemia, and cachexia decreased by more than 2% or 5% in the past 2 months or 6 months. 5. Uncontrolled hypertentsion, coronary heart disease, diabetes.

Locations (1)

Chinese PLA General Hospital

Beijing, Haidian, China

Outcomes

Primary Outcomes

Incidence of postoperative chronic pain

The incidence of chronic pain 6 month after operation

Time frame: 6 month after operation

Secondary Outcomes

Bedridden time

Postoperative bedridden time

Time frame: The postoperative duration up to 15 days

Fasting time

Postoperative fasting time

Time frame: The postoperative duration up to 15 days

Gastrointestinal decompression

Time of gastrointestinal decompression

Time frame: The postoperative duration up to 15 days

Data from ClinicalTrials.gov

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