Inspiratory Flow Parameters With Placebo Easyhaler and Placebo HandiHaler

Inclusion Criteria for subjects with COPD: 1. Written informed consent (IC) obtained. 2. ≥18 years of age. 3. Documented diagnosis of COPD. Inclusion Criteria for healthy volunteers: 1. Written informed consent (IC) obtained. 2. ≥18 years of age. 3. FEV1 at least 80% of the predicted value measured at screening. 4. Good general health ascertained by medical history. Exclusion Criteria for subjects with COPD: 1. Any chronic respiratory disease other than COPD. 2. Acute respiratory infection. 3. Concurrent participation in a clinical drug study. 4. Any medical condition (e.g. contraindications to spirometry) that in the opinion of the investigator could interfere with the interpretation of study results or cause a health risk for the subject if he/she participates in the study. E.g. any concomitant disease in clinically labile state judged by the investigator. 5. Severe milk allergy (lactose contains small amounts of milk proteins). Exclusion Criteria for healthy volunteers: 1. Evidence of a clinically significant cardiovascular, renal, hepatic, haematological, gastrointestinal, pulmonary, metabolic, endocrine, neurological or psychiatric disease within the previous 2 years. 2. Acute respiratory infection. 3. Concurrent participation in a clinical drug study. 4. Any medical condition (e.g. contraindications to spirometry) that in the opinion of the investigator could interfere with the interpretation of study results or cause a health risk for the subject if he/she participates in the study. 5. Severe milk allergy (lactose contains small amounts of milk proteins). Substudy: Patients with documented diagnosis of COPD aged 18 year or older participating the main study will be enrolled in this substudy. Written informed consent (IC) will be obtained.