Reducing the Effects of Aging on Cognition With Therapeutic Intervention of an Oral Nutrient (REACTION): A Pilot Trial

Inclusion Criteria: 1. English or Spanish speaking participants considered to have age-related cognitive decline based on the following criteria: A) RBANS (Verbal Memory Retention) A score ≥70% on list learning retention AND ≥80% on story memory retention and B) Subjective Cognitive Decline (SCD) 9-item brief screening tool score within the 25th percentile (SCD =1) and 75th percentile (SCD = 6) and C) MoCA ≥24 2. Age 55-89 3. Written informed consent provided by participant Exclusion Criteria: 1. Enrollment in any other clinical trial within 30 days prior to participation 2. Major Neurocognitive Disorder ("Dementia") according to the Diagnostic and Statistical Manual of Mental Disorders 5th Edition and/or NIAA Criteria 3. Use of any AD medication (e.g., cholinesterase inhibitors, NMDA antagonists), or OTC supplements or cognitive/memory enhancers 4. Use of omega-3 fatty acids in the 30 days prior to participation 5. Intake of Vitamins B6 and B12, folate, Vitamins C and E \> 300% RDI in the 24 days prior to participation 6. Concurrent major medical or neurological illness 7. Prior clinical history of stroke 8. History of substance abuse (e.g., alcohol, drugs) 9. Untreated Major Depressive Disorder that has not been in remission for at least 6 months prior to participation