Intense Pulsed Light in Meibomian Gland Dysfunctions

Centre Hospitalier Universitaire de Saint Etienne45 enrolled

Overview

Dry eye disease (DED) is an extremely common disease whose meibomian gland dysfunction is the main etiology. Polychromatic intense pulsed light (IPL) is a promising new therapeutic alternative but few clinical data have been published. A new IPL device has recently been marketed: LACRYSTIM (QUANTEL, France). The investigators have been using it in our clinical practice since June 2019. The investigators present a retrospective study on our first clinical results.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Dry Eye Syndromes Meibomian Gland Dysfunction

Interventions

intense pulsed light (usual practice)DEVICE

collection data : parameters used for each treatment session: duration of treatment session and intensity of intense pulsed light

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with Dry eye disease with meibomian gland dysfunction, preferentially mild to moderate, and having benefited from intense pulsed light treatment. * patient affiliated with a social security organization Exclusion Criteria: * patient with incomplete follow-up

Locations (1)

CHU de Saint Etienne

Saint-Etienne, France

Outcomes

Primary Outcomes

Lacrydiag in current clinical practice

The LacryDiag ocular surface analyzer is used for the diagnosis of dry eyes.

Time frame: 6 months

Secondary Outcomes

collection of adverse events

-data concerning the safety: presence or absence of adverse events during treatment or afterwards (burns, tingling, redness of skin ...)

Time frame: 6 months

Ocular Surface Disease Index questionnaire

measured in current clinical practice. This 12-item questionnaire assesses dry eye symptoms and the effects it has on vision-related function in the past week of the patient's life. The questionnaire has 3 subscales: ocular symptoms, vision-related function, and environmental triggers.

Time frame: 6 months

Slit lamp Photography x16 and x25

in current clinical practice

Time frame: 6 months

Oxford Score

measured in current clinical practice. The Oxford score is used to assess epithelial damage to the cornea and conjunctiva.

Time frame: 6 months

Break-up time Test

measured in current clinical practice. The measurement of the tear film rupture time determines the stability of the tear film, i.e. the degree of humidification of the eyes.

Time frame: 6 months

Schirmer Test

measured in current clinical practice. Determination of the quantity of tears produced.

Time frame: 6 months

Data from ClinicalTrials.gov

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