Per-oral Pyloromyotomy for Treating Infantile Hypertrophic Pyloric Stenosis

Shanghai Zhongshan Hospital20 enrolled

Overview

Infantile hypertrophic pyloric stenosis (IHPS) is the most common condition for surgical treatment in infant. Traditionally, laparoscopic or open pyloromyotomy are the standard treatments. However, because of severe dehydration, electrolyte disturbance, and malnutrition, these patients have lower tolerance about surgery and recover more slowly than usual. We are going to study the per-oral pyloromyotomy (POP), also named as gastric per-oral endoscopic myotomy (G-POEM), which showed promising results for adult gastroparesis, for a novel application of treating IHPS.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Infantile Hypertrophic Pyloric Stenosis Pyloromyotomy

Interventions

Per-oral pyloromyotomy (POP), also named as gastric per-oral endoscopic myotomy (G-POEM), for treating infantile hypertrophic pyloric stenosis (IHPS) has the following steps: mucosal incision, creation of submucosal tunnel, full-thickness pyloromyotomy, closure of the mucosal entry.

Eligibility

Sex: ALLMax age: 3 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical diagnosis of pyloric stenosis with or without sonographic confirmation. Exclusion Criteria: * Comorbid conditions that could affect postoperative recovery. * Needed an additional procedure during the same anaesthetic.