Diagnosis of active and latent pulmonary tuberculosis, as well as extrapulmonary tuberculosis, is still a major challenge of TB control in China. This observational study aims to evaluate TB-antigen responsive T cell markers in the diagnosis of tuberculosis and extrapulmonary tuberculosis and try to find new prompt and cost-effective laboratory tests for active TB screening.
The enrolled patients will be grouped into active or latent tuberculosis according to the bacteriological evidence of TB. The TB-antigen responsive T cell markers will be examined. The performance of each T cell marker for the diagnosis of active TB will be systematically evaluated.
Study Type
OBSERVATIONAL
Enrollment
500
A blood test including a series of T cell markers which are responsive to TB antigens
Shanghai Pulmonary Hospital
Shanghai, Shanghai Municipality, China
RECRUITINGPositive rate and negative rate
Evaluation of the positive rate and negative rate for each T cell marker
Time frame: 2-3 month after sampling
Receiver operating characteristic curve
The AUC of each T cell marker will be analyzed and compared
Time frame: 2-3 month after sampling
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