Sepsis is a life-threatening complication of infection that can be difficult to recognize and treat promptly. Timely administration of antibiotics for emergency department (ED) patients with sepsis is challenging. The goal of this study is to determine the potential effectiveness and unintended consequences of reorganizing ED care for patients with suspected sepsis.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE
Enrollment
180,402
Implementation of a coordinated, structured, multidisciplinary team-based protocol for initial evaluation and treatment of ED patients with suspected sepsis.
Intermountain Medical Center
Murray, Utah, United States
Utah Valley Hospital
Provo, Utah, United States
Dixie Regional Medical Center
St. George, Utah, United States
Door-to-antibiotic Time
Time from sepsis patients' emergency department arrival to intravenous (or equivalent) antibiotic initiation
Time frame: Up to 24 hours from ED arrival (an average of 3 hours)
All-cause 30-day Mortality
Sepsis patient death on or before the 30th day after ED arrival
Time frame: 30 days after ED arrival
All-cause 1-year Mortality
Sepsis patient death on or before the 365th day after ED arrival
Time frame: 1 year after ED arrival
All-cause In-hospital Mortality
Sepsis patient death prior to hospital discharge
Time frame: From the time of admission to hospital discharge (up to 1 year, average 14 days)
Hospital Charges
Amount charged to sepsis patient for their medical care during index ED visit and associated hospitalization
Time frame: From the time of admission to hospital discharge (up to 1 year, average 14 days)
Hospital Length of Stay
Length of time from sepsis patients' ED arrival until hospital discharge
Time frame: From the time of admission to hospital discharge (up to 1 year, average 14 days)
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