Platelet Rich Plasma Injection Into Ovary of Patients With Premature Ovarian Insufficiency

Tanta University16 enrolled

Overview

All encountered cases with POI will be assessed and examined then investigated. Eligible cases will be included in the study

Patients will be subjected to injection of autologous PRP inside the ovary about 0.5-1 mml by laparoscopy

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Premature Ovarian Failure

Interventions

PRP injection inside the ovary by laparoscoy. The injection volume is 2 mlPROCEDURE

intraovarian injection of 2 mml of PRP by laparoscopic guide

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 35 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Premature ovarian insufficiency diagnosed by: * FSH\> 40 Amenorrhea Menopuasal symptoms Infertility Exclusion Criteria: * Refusal to participate Secondary POI due chemotherapy, surgery, or radiotherapy Previous treatment with PRP

Locations (1)

Adel Elgergawy

Tanta, Egypt

Outcomes

Primary Outcomes

Resumption of ovarian hormonal function

Measurement of Estradiol level on Day 3 of cycle

Time frame: 3-6 months

Resumption of ovarian folliclugenesis

Assessment of the presence of oocytes by trans vaginal ultrasound on day 3

Time frame: 3-6 months

Secondary Outcomes

Resumption of menstruation

Occurrence of Menstruation after secondary amenrorrhea by questionnaire

Time frame: 3-6 months

Fertility potential

Potential to get pregnant after ICSI procedure

Time frame: 3-6 months

Data from ClinicalTrials.gov

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