The Water Intake Trail and Primary Aldosteronism Postoperation(WIT-PAP)

Inclusion Criteria: * Age 18-75 years * Able to provide informed consent and willing to complete follow-up visits. * Estimated glomerular filtration(eGFR) rate over 60 ml/min/1•73 m² * According to the Guideline of Primary Aldosteronism, unilateral PA has been diagnosed and unilateral adrenalectomy has been completed * Urine volume can be recorded consciously, and daily drinking water volume is less than 2L/d Exclusion Criteria: * Pregnant or breastfeeding * Diagnosed with other types of chronic kidney diseases, such as IgA nephropathy, lupus nephritis, etc. * History of malignant tumor * History of kidney stones in past 5 years * Kidney transplant within past six months (or on waiting list) * Less than two years life expectancy * Serum sodium \<130 mEq/L without suitable explanation or Serum calcium \>2.6 mmol/L without suitable explanation * Currently taking hydrochlorothiazide \>25 mg/d, indapamide \>1.25 mg/d, furosemide \>40 mg, or metolazone \>2.5 mg/d * Poor blood pressure control (systolic pressure\>180mmHg or diastolic pressure\> 110mmHg) * Alcoholics, drug addicts, and people with mental disorders who cannot cooperate * Patient is under fluid restriction (\<1.5 L a day) for kidney disease, heart failure, or liver disease, AND meets any of the following criteria: i) end stage of the disease (heart left ventricular ejection fraction \<40%, NYHA class 3 or 4, or end stage cirrhosis) , ii) hospitalization secondary to ACS,heart failure, stroke,ascites and/or anasarca ,iii)Severe anemia (Hb\<60g/L)