Pterygium is wing-shaped, vascular, fleshy growth that originates on the conjuntiva and that can spread to the corneal limbus and beyond The surgical exeresis with autologous conjunctival autograft technique is the treatment of choice. Commercially available fibrin glue has been used preferentially for graft fixation due to its benefits compared to sutures; However, its cost and the risk of inflammatory immune reaction limit the its use. There are few studies about autologous fibrin glue. OBJECTIVE: To determine the efficacy of autologous fibrin glue preparation in patients undergoing pterygium resection surgery. To compare with autologous conjunctival graft fixation with suture. This is a randomized clinical trial. Two patient groups will undergo pterygium excision surgery. Group 1 will have autologous conjunctival graft fixation with autologous fibrin glue and group 2 will have suture graft fixation using 10.0 mononylon. Early and late postoperative surgical results as well as complication rates will be analyzed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
64
Conjunctival graft fixation with autologous fibrin glue
Graft fixation using 10.0 mononylon
Santa Casa de Misericórdia
Porto Alegre, Rio Grande do Sul, Brazil
Pterygium Recurrence
Recurrence in 6 months
Time frame: 6 months
Autograft Retraction
Graft detachment or retraction
Time frame: Postoperative day 1, 7, 21 and 30
Postoperative Pain
Presence Pain measured by a five-point scale, in which 0 means absence of symptom; 1 means easily tolerable symptom; 2 means symptom causing some discomfort; 3 means symptom partially interfering with usual activities and 4 means symptom completely interfering with usual activities
Time frame: Postoperative day 1, 7, 21 and 30
Graft Edema
Graft edema (1-4).
Time frame: Postoperative day 1, 7, 21 and 30
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