Milrinone on Cardiac Performance During Off-pump Coronary Artery Bypass Surgery

Konkuk University Medical Center20 enrolled

Overview

The purpose of this study is to analyze the changes in cardiac performance before and after milrinone administration in order to find out whether milrinone improves LV performance in patients undergoing coronary artery bypass surgery.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Ischemic Heart Disease

Interventions

Milrinone InjectionDRUG

giving IV milrinone: 50 mcg/kg loading dose by IV push over 10 minutes, then 0.375-0.75 mcg/kg/min IV

Eligibility

Sex: ALLMin age: 20 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patient agree and provide written informed consent. * patient undergoing elective coronary artery bypass graft surgery * preoperative LV EF\>50% (TTE) Exclusion Criteria: * preoperative cardiac dysrhythmia * preoperative IABP * use of other inotropic agents

Outcomes

Primary Outcomes

TMAD of ticuspid annulus during early relaxation

Time frame: 15 mini after milrinone administration

Secondary Outcomes

global longitudinal strain of the right ventricle

Time frame: 15 mini after milrinone administration

left ventricular ejection fraction

Time frame: 15 min after milline administration

global longitudinal strain of the left ventricle

Time frame: 15 min after milline administration

Data from ClinicalTrials.gov

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