The EUA Urolithiasis Guidelines Panel meta-analysis suggest that mPNL is at least as efficacious and safe as sPNL for the removal of renal calculi. However, the quality of the evidence was poor, drawn mainly from small studies, the majority of which were single-arm case series, and only one of which was RCT. The risks of bias and confounding were high, highlighting the need for more reliable data from RCTs. So, the Panel recommended for more clinical research . The aim of this study is to compare between PNL and mPNL through a randomized controlled trial.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
210
MINIPERCUTANEOUS NEPHROLITHOTOMY USING NEPHROSCOPY 15 FR, LASER DUSTING OF THE STONE, NEPHROSTOMY TUBE 12 FIXATION
PERCUTANEOUS NEPHROLITHOTOMY USING NEPHROSCOPY 24 FR, ULTRASOUND OR LITHOCLAST DISINTEGRATION OF THE STONE AND FORCEPS EXTRACTION OF THE FRAGMENTS, NEPHROSTOMY TUBE 22 FIXATION
Urology and Nephrology Center
Al Mansurah, Aldakahlia, Egypt
Assessment of stone free rate (SFR)
defined as less than 4mm by non contrast computed tomography
Time frame: 2 years
assessment of haemoglobin loss
measured by haemoglobin change pre and postoperative (measured by grams/ deciliter)
Time frame: 2 years
assessment of pain
measured by visual analogue scale
Time frame: 2 years
assessment of renal function
measured by serum creatinine measured by Milligram/ deciliter
Time frame: 2 years
assessment of patient satisfaction
measured by freiburg index of patient satisfaction
Time frame: 2 years
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