Innovative Food Structures to Enhance Nutrient Bioavailability

University College Dublin80 enrolled

Overview

This randomized controlled trial (RCT) will compare the change in vitamin D status (25-hydroxyvitamin D nmol/L) after a 4 week intervention with 4 groups: 1. Vitamin D enriched (20ug) olive oil emulsion drink 2. Vitamin D enriched (20ug) coconut oil emulsion drink 3. Placebo emulsion drink 4. Vitamin D supplement (20ug) Participants will be randomized to 1 of 4 intervention group. Hypothesis 1: 25-hydroxyvitamin D concentrations are higher in the olive oil emulsion drink group compared to the placebo emulsion drink group post intervention. Hypothesis 2: 25-hydroxyvitamin D concentrations are higher in the olive oil emulsion drink group compared to the coconut oil emulsion drink group post intervention.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

Conditions

Vitamin D Deficiency Aging Well

Interventions

Vitamin D enriched (20 mcg/day) olive oil emulsion drink. 30 mL drink daily

Vitamin D enriched (20 mcg/day) coconut oil emulsion drinkDIETARY_SUPPLEMENT

Vitamin D enriched (20 mcg/day) coconut oil emulsion drink 30 mL drink daily

Placebo coconut oil emulsion drinkDIETARY_SUPPLEMENT

Placebo coconut oil emulsion drink 30 mL drink daily

Vitamin D supplement (20 mcg/day)DIETARY_SUPPLEMENT

Vitamin D supplement (20 mcg/day) Pill consumed daily

Eligibility

Sex: ALLMin age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: • Healthy adults Exclusion Criteria: * Pregnant/lactating * Smokers * Individuals who are not free-living * An inability to read, write or understand English * Following a strict diet for any reason, insulin dependent diabetes, coeliac etc. * Disease that requires chronic therapeutic nutritional or medical treatment * Those with conditions that may affect kidney function * Those with osteoporosis * Those taking supplemental vitamin D * Those who have been on a sun holiday in the last 2 months * Those with a milk protein allergy or lactose intolerance

Locations (1)

University College Dublin

Dublin, Ireland

Outcomes

Primary Outcomes

Vitamin D status

Change in vitamin D status measured as serum 25-hydroxyvitamin D (nmol/L)

Time frame: Baseline to 28 days

Data from ClinicalTrials.gov

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