Extracoporeal Shock Wave Therapy (ESWT) for the Treatment of Detrusor Underactivity/ Underactive Bladder (DU/UAB)

Inclusion Criteria: 1. Adult male or female, at least 20 years of age. 2. History of UAB (defined as bothersome chronic incomplete bladder emptying) for at least 3 months documented in the medical record with recurring UAB symptoms. 3. No UAB symptom relief (unresponsiveness) with previous used medications and/or other treatments. 4. Voiding difficulty (complains of difficulty emptying the bladder). 5. UAB consistent with diabetes, MS, Parkinson's disease, or aging idiopathic. 6. Post void residual ≥ 100 mL. 7. Bladder capacity \> 200 mL and \< 800 mL. 8. Pressure flow Urodynamic testing demonstrating impaired detrusor contractility or areflexia without evidence of BOO, with maximum detrusor pressure Pdet at Qmax (Pdet@Qmax) of \< 20 cmH2O and Maximum flow rate (Qmax) \< 15 mL/sec for female, and BCI \< 100 and BOOI \< 40 for male. 9. Total UAB Questionnaire Score ≥ 3. 10. Females of child-bearing potential agree to use reliable birth control for the entire study duration. 11. Willing and capable of understanding and complying with all requirements of the protocol, including proper completion of the voiding diaries and self-administered questionnaires. 12. Free of active urinary tract infection. 13. Free of bladder outlet obstruction on enrollment. 14. Patient or his/her legally acceptable representative has signed the written informed consent form. 15. Subject on clean intermittent catheterization (CIC) should have been on CIC for at least 1 month and should be able to void spontaneously and not be completely dependent on CIC. Exclusion Criteria: 1. Female patients who is pregnant, lactating, plans to become pregnant, or with child-bearing potential without contraception. 2. Simultaneously participating in another investigational drug or device study or use of any investigational drug(s) or therapeutic device(s) within 3 months preceding enrollment 3. Has been treated with an investigational device, drug, or procedure for UAB within the last 3 months. 4. History of cancer in pelvic organs, ureters, or kidneys or any cancer that has undergone treatment within the past 12 months. 5. Medical condition or disorder that may limit life expectancy or that may cause protocol deviations (e.g. unable to perform self-evaluations/accurately report medical history, and/or urinary symptoms). 6. History of spinal cord injury affecting urinary function. 7. Patients with uncontrolled acute urinary tract infection. An active urinary tract infection as evidenced by positive urine culture at the time of baseline assessment. If a UTI is confirmed in the baseline sample (e.g., positive urine culture containing \> 100,000 cfu/mL in midstream urine), the run-in period should be stopped. After successful treatment of the UTI, the patient can be rescreened and if eligible enroll in the study. If the patient has asymptomatic bacteriuria (i.e., a positive urine culture without clinical signs and symptoms of a UTI), the patient should not be excluded. 8. Currently taking medication(s) that may affect urination, including prescription drugs (i.e. anticholinergics, tricyclic antidepressants, bethanechol), over the counter drugs, dietary and/or herbal supplements, adrenergic antagonists. Alpha adrenergic blockers are allowed to use in a stable condition (longer than 1 month and keeping use during the study period). 9. Pelvic organ prolapses beyond the introitus (e.g., cystocele, rectocele). 10. Prior mesh surgery for stress urinary incontinence or pelvic prolapse. 11. Any other condition which per investigators' judgement, may affect the patient's safety (e.g. significant cardiovascular disease, asthma or other breathing disorders). 12. Patients with bladder outlet obstruction on enrollment. 13. Patients with any contraindication to be urethral catheterization during diagnostic test or treatment or follow-up period. 14. Patients have laboratory abnormalities at screening including: ALT \> 3 x upper limit of normal range AST \> 3 x upper limit of normal range Serum creatinine level \> 2 x upper limit of normal range. 15. Patients with any other serious disease considered by the investigator not in the condition to enter the trial. 16. Patients with cortisone treatment 6 week before first LESW therapy. Other single item of Lab examination also can be retested per Investigator's discretion if abnormality. Patient will be rescreened and randomized into the study once confirmed eligible.