This is an open-label, multicenter, extension study to evaluate the long-term safety and efficacy of BeiGene or BeOne investigational drugs in participants with advanced malignancies who participated in a prior BeiGene- or BeOne-sponsored clinical study (parent study).
For the purposes of this study, "study treatment" will refer to all investigational agents. A parent study is defined as the original BeiGene- or BeOne-sponsored clinical trial in which the participant was initially enrolled and received BeiGene or BeOne investigational drugs (with or without other treatments). Note: Our company, previously known as BeiGene, is now officially BeOne Medicines. Because some of our older studies were sponsored under the name BeiGene, you may see both names used for this study on this website.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
404
Administered intravenously.
Administered orally.
Administered orally.
Number of Participants with Immune-Mediated Adverse Events, Serious Adverse Events, and Adverse Events Grade 3 or Higher
Safety as assessed by the number of participants with immune-mediated adverse events (imAEs), ≥ Grade 3 adverse events, and serious adverse events.
Time frame: up to 7 years
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Administered orally.
Administered intravenously.
Administered intravenously.
Administered orally.
Administered orally.
Administered intravenously.
Administered intravenously.
Administered intravenously.
Administered orally.
Administered intravenously.
Mount Sinai Medical Center Braman Comprehensive Cancer Center
Miami, Florida, United States
Memorial Sloan Kettering Cancer Center Mskcc
New York, New York, United States
Tennessee Oncology, Pllc Nashville
Nashville, Tennessee, United States
Baylor Research Institute
Dallas, Texas, United States
Prince of Wales Hospital
Randwick, New South Wales, Australia
Northern Cancer Institute
St Leonards, New South Wales, Australia
Calvary Mater Newcastle
Waratah, New South Wales, Australia
Icon Cancer Centre South Brisbane
South Brisbane, Queensland, Australia
The Queen Elizabeth Hospital
Woodville South, South Australia, Australia
Monash Health
Clayton, Victoria, Australia
...and 96 more locations