Many guidelines at home and abroad advocate that arteriovenous fistula should be the first choice of permanent vascular access, but it is easy to form thrombus in a short time after arteriovenous fistula molding, resulting in internal fistula stenosis or occlusion. In this study, the investigators plan to screen the patients with arteriovenous fistula in the blood purification center of our hospital. Through the study design of random grouping and open label, the investigators will discuss the use of low molecular weight heparin or warfarin to prevent thrombosis in a short period of time after arteriovenous fistula operation. According to the research results, the investigators will understand efficacy and safety of short-term postoperative anticoagulant therapy to prevente thrombosis in arterovenous fistula.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
287
patients began to use low molecular weight heparin or warfarin sodium tablets.
no anticoagulant was used after operation.
The First Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, China
Blood flow of arteriovenous fistula
Blood flow of arteriovenous fistula during hemodialysis from 6 months after operation
Time frame: up to 12 months
arteriovenous fistula dysfunction or occlusion
The proportion of arteriovenous fistula dysfunction or occlusion
Time frame: up to 12 months
Active bleeding events
such as,bleeding of surgical wound, intracranial, digestive tract and urinary tract, ecchymosis and ecchymosis of skin.
Time frame: up to 12 months
arteriovenous fistula dysfunction or occlusion
The time of arteriovenous fistula dysfunction or occlusion
Time frame: up to 12 months
AVF Maturation Failure AVF Maturation Failure AVF Maturation Failure AVF Maturation Failure AVF maturation failure
AVF maturation failure two months postoperatively
Time frame: up to 2 months
coagulation index
Change of coagulation index
Time frame: up to 12 months
Platelet
Changes of platelet indexes
Time frame: up to 12 months
Number of hospitalization
Number of hospitalization due to arteriovenous fistula thrombosis.
Time frame: up to 12 months
Death
Death from any cause
Time frame: up to 12 months
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