Our study is intended to compare optimal muscle tension management or conventional anesthetic management in laparoscopic cholecystectomy about surgical condition during the surgery and other conditions after surgery at POR.
This study is intended to recruit 70 patients undergoing laparoscopic cholecystectomy, whom will be randomized to receive optimal muscle tension management or conventional anesthetic management without optimal muscle tension management. Our primary hypothesis is that optimal muscle tension management provides improved surgical conditions and less intra-abdominal pressure required. The secondary endpoints include surgical duration, intraoperative complications, total amount of muscle relaxants, respiratory and hemodynamic changes during surgery, extubation time and any events during post-anesthetic recovery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
70
including TOF monitor and reversal of neuromuscular blockade agent : sugammadex
National Taiwan University Hospital, Hsin-Chu Branch
Hsinchu, Taiwan
Surgical condition
Surgeon describe CO2 inflation condition by 4 point King Score (1-4). 1. excellent 2. good 3. acceptable 4. poor or unacceptable
Time frame: 5 minutes
Peak inspiratory pressure during surgery
Peak inspiratory pressure during surgery
Time frame: 1 hour
Mean blood pressure
Mean blood pressure during the CO2 inflation
Time frame: Every 5 mins
Total surgical time
Total surgical time
Time frame: 1 hour
Total Rocuronium doses during surgery
Total Rocuronium doses during surgery
Time frame: 1 hour
Pain score at Postoperative room
describe by 11 points Numeric rating scales (0-10). From 0 which means "no pain" to 10 means "worst pain"
Time frame: 1 hour
Heart Rate
Every beat per minutes heart rate during CO2 inflation
Time frame: every 5 mins
Respiratory complications
Record any respiratory complications including desaturations (\<95%, more than 30 seconds, Rispiratory rate \< 8), aspiration or airway obstruction
Time frame: Every 5 mins
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