Can VI-RADS/ADC Accurately Stage Bladder Cancer??

N/AActive Not RecruitingNCT04167631

Mansoura University150 enrolled

Overview

Vesical Imaging-Reporting And Data System (VI-RADS) is proposed for predicting muscle invasive bladder cancer (MIBC) using multi-parametric MRI. However, No validation study on VI-RADS has been reported yet. Apparent diffusion coefficient (ADC) values on diffusion-weighted MRI are reportedly significantly lower in MIBC than those in non-MIBC(NMIBC). We aim to examine the accuracy of VI-RADS for predicting MIBC in final histopathology specimen. To assess whether incorporating ADC into VI-RADS improves the MIBC predictive accuracy of VI-RADS

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

150

Conditions

MRI Contrast Media Adverse Reaction Bladder Cancer Bladder Disease

Interventions

Multi-parametric MRIRADIATION

Vesical Imaging-Reporting And Data System (VI-RADS) for predicting non-muscle invasive bladder cancer (NMIBC) using multi-parametric MRI.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients diagnosed at the out-patient cystoscopy with papillary or small nodular bladder tumour Exclusion Criteria: * fungating lesions * beyond the scope of enbloc resection

Locations (1)

Urology and Nephrology Center

Al Mansurah, Aldakahlia, Egypt

Outcomes

Primary Outcomes

Vesical Imaging-Reporting And Data System (VI-RADS) for discriminating muscle invasive bladder cancer (MIBC) from non-muscle invasive bladder cancer (NMIBC) using multi-parametric MRI.

assessed by final histopathology specimen retrieved by enbloc transurethral resection of bladder tumors (ERBT)

Time frame: 18 months

Data from ClinicalTrials.gov

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