It is commonly recommended that patients should refrain from driving for 24 hours after sedation for endoscopy，however，this recommendation has been queried recently．To investigate the effect of sedation on early postoperative cognitive function in patients undergoing endoscopy.
One hundred adult patients undergoing sedative esophagogastroduodenoscopy ( EGD) were randomly recruited，and another 100 adult patients undergoing conventional（without sedation） EGD were served as controls． All patients had an education level more than 9 years． Cognitive function was assessed by Montreal Cognitive Assessment（MoCA）1 week before EGD exam, 10 mins before propofol sedation or the beginning of endoscopic procedure, 30mins after EGD exam, and 2 week after exam.
Study Type
OBSERVATIONAL
Enrollment
200
Department of Gastroenterology, Renji Hospital, Shanghai Institute of Digestive Diseases, Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, China
NCT-A test outcome measure
the score of NCT-A test for each patient is not less than that in the baseline.
Time frame: 30 minutes
DST test outcome measure
the score of DST for each patient is not less than that in the baseline.
Time frame: 30 minutes
number cancellation test outcome measure
the score of number cancellation test for each patient is not less than that in the baseline.
Time frame: 30 minutes
heart rate outcome measure
heart rate less than 50 time per minute
Time frame: 5 minutes
SpO2 outcome measure
SpO2 less than 90%
Time frame: 5 minutes
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