This study project is an observational trial involving 90 patients suffering from male type infertility. The patients are divided in two groups (45 patients per group) based on their body mass index (BMI).
This study (Tampere Infertility Microbiome Project, TIMP) aims to clarify the differences in the microbiome variety between obese and normal-weight patients. The first group will consist of patients with the body mass index (BMI) over 30 kg/m², while the second group will include patients with a healthy weight BMI under 25. The samples will be collected at the time of embryo transfer and analyzed in a laboratory specialing in next-generation sequencing (NGS) techniques.
Study Type
OBSERVATIONAL
Enrollment
91
Samples from TIMP microbiome project will be analyzed with NGS techniques.
Tampere University Hospital
Tampere, Finland
Microbiome variety between groups
This study aims to investigate differences of endometrium microbiome and continuum of microbiota from anal to reproductive tract site between obese and normal-weight patients. Samples will be collected at the time of embryo transfer using embryo transfer catheter. The study will also examine pregnancy outcomes and microbiome differences in pregnant patients.
Time frame: through study completion, 1-2 years from the starting date
Ongoing pregnancy rate
Ongoing pregnancy rate
Time frame: up to 2-3 months
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