We will need about 36 participants for this study. Volunteers might be able to participate if: * they have bad noninfectious keratitis * early treatments failed or were not well tolerated Participants will be in the study for about 22 weeks: * 4 weeks for tests to see if the study might be good for them * 12 weeks of treatment with Acthar gel * 4 weeks to wean off Acthar gel and follow-up with the doctor
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
36
Acthar gel for subcutaneous injection
Cornea and Cataract Consultants of Arizona
Phoenix, Arizona, United States
Global Research Management, Inc.
Glendale, California, United States
Eye Research Foundation
Newport Beach, California, United States
Number of Participants Who Improved on the Impact of Dry Eye on Everyday Life (IDEEL) Scale [Using the Symptom Bother Module at Week 12]
A 12-point score reduction on the 100-point symptom bother module indicates a clinically important reduction of bothersome dry eye symptoms.
Time frame: Week 12
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Eye Care Institute
Louisville, Kentucky, United States
Andover Eye Associates
Raynham, Massachusetts, United States
Vita Eye Clinic
Shelby, North Carolina, United States
Scott & Christie and Associates, PC
Cranberry Township, Pennsylvania, United States
Total Eye Care, P.A.
Memphis, Tennessee, United States
Advancing Vision Research, LLC
Nashville, Tennessee, United States