Sarcopenia is a pathophysiological process associated with aging and some metabolic conditions characterized by progressive muscle tissue loss, which may lead to loss of strangth and performance and increase risk of falls and fractures, physical disability and premature death. Therefore, it is necessary to identify personalized programs of physical activity and supplementation for elderly population in order to improve their physical functions, muscle strengh and body composition. With the present project we aime to assess the effect of a feasible home-based exercise program coupled with food supplementation to improve muscle strength, muscle volume and muscle physical performance potentially associated with sarcopenia in elderly people.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
16
Home-based physical activity program
Home-based physical activity program and amminoacid supplementation
No intervention
IRCCS Istituto Ortopedico Galeazzi
Milan, Italy
Lower limb strength
Assessed by chair stand test
Time frame: Baseline and Week 24
Body composition
Assessed by Whole-body dual energy X-ray absorptiometry
Time frame: Baseline and Week 24
Quantify thigh cross sectional area
Assessed by Dixon magnetic resonance imaging
Time frame: Baseline and Week 24
Maximum isometric force that a hand can squeeze
Assessed by Hand Grip Strength test
Time frame: Baseline and Week 24
Maximal Isometric Strength of Knee flexors and extensors
Assessed by a belt-stabilized dynamometer
Time frame: Baseline AND Week 24
Dynamic balance and gait deficits
Assessed by mini-BESTest
Time frame: Baseline and Week 24
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