High flow nasal cannula (HFNC) ventilation therapy was found to improve the severity of obstructive sleep apnea in non-stroke subjects. The investigators hypothesized that HFNC might be effective in stroke patients with dysphagia who needed nasogastric tube feeding and can not receive continuous positive airway pressure ventilation for obstructive sleep apnea.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
22
High-flow nasal cannula (HFNC) ventilation therapy: supply heated \& humidified air up to 60 L/min of flow; effects: positive end expiratory pressure effect, humidification.
Chang Gung Memorial Hospital, Keelung
Keelung, Taiwan
apnea-hypopnea index
respiratory inductance plethysmography sum (RIPsum) without calibration to score apnea and hypopnea events (American Academy of Sleep Medicine alternative criteria)
Time frame: once at polysomnography study night when receive high flow nasal cannula titration study
oxyhemoglobin desaturation index
number of times per hour of sleep that the blood's oxygen saturation level drops by ≥ 3% from baseline
Time frame: once at polysomnography study night when receive high flow nasal cannula titration study
pulse wave velocity
velocity (m/s) measured by SphygmoCor CPV system
Time frame: baseline and 1 week after high flow nasal cannula therapy
heart rate variability
measured by QHRV system (Medeia Ltd.)
Time frame: baseline and 1 week after high flow nasal cannula therapy
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