The aim of this study to investigate and compare functional capacity with different tests and to evaluate the relationship between functional capacity and quality of life during acute pulmonary exacerbation in children with cystic fibrosis. Exercise tests associated with prognostic values in CF patients and decreased exercise capacity has been correlated with a reduction in health-related quality of life. Pulmonary functions, functional capacity and quality of life will examine in this study.
This study will be participated children with cystic fibrosis who will diagnosed acute pulmonary exacerbation. Patients' pulmonary function test, functional capacity will be assess and record at hospital admission and hospital discharge and outpatient clinic control. Quality of life will be evaluated at only outpatient clinic control . Pulmonary function test will be assessed with spirometry, functional capacity will be evaluated with 1-minute sit to stand test and 3-minute step test. And quality of life will be evaluated Cystic Fibrosis Questionnaire-Revised (CFQ-R).
Study Type
OBSERVATIONAL
Enrollment
26
Childrens will complete 1-minute sit to stand test and 3 minute step test and quality of life questionnaire.
Hacettepe University
Ankara, Turkey (Türkiye)
RECRUITING1 minute sit to stand test (STS) repetitions
number of STS completed at hospital admissions, hospital discharge and outpatient time
Time frame: November 2019- January 2021
3 minute step test
number of completed step at hospital admissions, hospital discharge and outpatient time
Time frame: November 2019- January 2021
pulmonary functions
pulmonary functions assessment via spirometry
Time frame: November 2019- January 2021
Quality of life assesment
Cystic Fibrosis Questionnaire-Revised (CFQ-R) included 4 different age. These versions are teen/adult version,child version,parent version for children, preschool version. Scores range from 0 to 100, with higher scores indicating better health. This questionnaire will be filled only once.
Time frame: November 2019- January 2021
Maximal heart rate
maximal heart rate during 3-minute step test
Time frame: November 2019- January 2021
Heart rate
difference pre and post test heart beat number
Time frame: November 2019- January 2021
oxygen saturation
difference pre and post test percentage of oxygen saturation
Time frame: November 2019- January 2021
dyspnea
difference pre and post test breathlessness with Visual Analogue Scale (VAS).Scores range from 0 to 10, with higher scores indicating worse outcome.
Time frame: November 2019- January 2021
quadriceps fatigue
difference pre and post test quadriceps fatigue with Visual Analogue Scale (VAS).Scores range from 0 to 10, with higher scores indicating worse outcome.
Time frame: November 2019- January 2021
fatigue
difference pre and post test fatigue with Visual Analogue Scale (VAS).Scores range from 0 to 10, with higher scores indicating worse outcome.
Time frame: November 2019- January 2021
hospitalization frequency
number of hospitalization per year
Time frame: 1 year
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