The purpose of this study is to evaluate the safety and efficacy of IGIV 10% in patients with autoimmune encephalitis
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
23
IGIV 10%(400mg/kg) QD for 5 consecutive days administrated intravenously.
Seoul National University Hospital
Seoul, South Korea
Chage of mRS(The Modified Rankin Scale) score; 0(better) to 6(worse)
Change of mRS score 7 days and 28 days after IP administration compared with baseline(before IP administration)
Time frame: 28 days
Chage and improvement of mRS(The Modified Rankin Scale) score; 0(better) to 6(worse)
Change and improvment of mRS score 14 days and 28 days after IP administration compared with baseline(before IP administration)
Time frame: 28 days
Chage and improvement of Glasgow coma scale(GCS); 3(worse) to 15(better)
Change and improvment of Glasgow coma scale(GCS) 7 days, 14 days and 28 days after IP administration compared with baseline(before IP administration)
Time frame: 28 days
Chage and improvement of Clinical Global Impression Scale-Severity; 1(better) to 7(worse)
Change and improvment of Clinical Global Impression Scale-Severity 7 days, 14 days and 28 days after IP administration compared with baseline(before IP administration)
Time frame: 28 days
Chage and improvement of Clinical Global Impression Scale-Impovement; 1(better) to 7(worse)
Change and improvment of Clinical Global Impression Scale-Improvement 7 days, 14 days and 28 days after IP administration compared with baseline(before IP administration)
Time frame: 28 days
Chage and improvement of CASE(Clinical Assessment scale of Encephalitis) score; 0(better) to 27(worse)
Change and improvment of CASE score 7 days, 14 days and 28 days after IP administration compared with baseline(before IP administration)
Time frame: 28 days
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The relationship
The relationship between neurological scale
Time frame: 28 days