Pain is a global public health issue and represents the most common reason for both physician consultation and hospital admissions . When unrelieved or poorly controlled, it is associated with medical complications, poor patient satisfaction and increased risk of developing chronic pain. Dexketoprofen is a new NSAID treating acute postoperative pain and when it combined with tramadol may have a better effect. The purpose of this study is to evaluate the analgesic effect of the oral use of the combination of dexketoprofen/tramadole on the reduction of postoperative pain after total hip arthroplasty with minimal invasive anterior approach (AMIS).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
226
Postoperatively patients in Group A received the oral combination dexketoprofen/tramadol for the treatment of acute postoperative pain the first 72h
Patients in group B received IV tramadol 75mg every 8h
Patients in group B received IV paracetamol 1g every 8h
300mg ropivacaine as periarticular injection in a dilution of 100ml n/s 0,9% was done by the orthopedic surgeon in all patients
10-15mg levobupivacaine was done subarachnoidal for spinal anesthesia
Elena Nikolakopoulou
Athens, Kifissia, Greece
Pain score in 8hours
Pain score with the visualised analogue scale in 8hours
Time frame: 8 hours
Pain score in 24hours
Pain score with the visualised analogue scale in 24 hours
Time frame: 24 hours
Pain score in 48 hours
Pain score with the visualised analogue scale in 48 hours
Time frame: 48 hours
Pain score in 72 hours
Pain score with the visualised analogue scale in 72 hours
Time frame: 72 hours
Total analgesic consumption
Total analgesic consumption as rescue analgesia the first 24 hours
Time frame: 24 houra
Side effects
All the side effects of the drug the first 72 hours
Time frame: 72 hours
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