Bronchopulmonary dysplasia of premature infants is a common respiratory disease in premature infants. Long-term complications such as recurrent respiratory infection and abnormal lung function may occur in the survivors, and may increase the risk of dysplasia of the nervous system. In the past 30 years, although the monitoring and treatment technology of premature infants has been significantly improved, the incidence of BPD still shows no downward trend, and effective treatment and prevention methods for BPD are still lacking. The progress of clinical research on BPD is slow, one of the important reasons is that the definition of BPD is still not consistent, and its diagnostic and grading standards lack objectivity. To summarize the development of diagnostic criteria for BPD in the past 30 years, there are still the following disadvantages. 1. 2. In the above study, all proposed alternative BPD classification standards did not completely separate HFNC and NIV. In view of this, this study separated HFNC(High Flow Nasal Cannula Oxygen) and other NIV(Non-Invasive Ventilation) to form a new revised BPD classification standard. On this basis, a nested case-control study was conducted to compare the differences between the newly proposed classification standards and NICHD(National Institute of Child Health and Human Development) standards in 2001, Rosemary standards in 2018 and Jensen standards in predicting long-term respiratory outcomes and other systemic complications in premature infants, so as to provide a standard for more accurate diagnosis and evaluation of BPD in premature infants.
Study Type
OBSERVATIONAL
Enrollment
322
no intervention
Children's hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, China
Respiratory Adverse Outcomes
Respiratory adverse outcomes include all types of neonatal lung diseases
Time frame: up to 18 months after birth
Growth Restriction
height, weight or head circumference \<3rd percentile for corrected gestational age and sex, growth percentiles defined using the World Health Organization Child Growth Standards
Time frame: up to PMA 18-24 months
Days of Oxygen Supplement
days during which the infants were given oxygen supplement
Time frame: up to 18 months after birth
Physical Development Outcome
including length, weight, head circumference
Time frame: up to 18 months after birth
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