Effect of Intraoperative Dexamethasone on Post-op Dry Eye

SR Cornea Consultants40 enrolled

Overview

To compare the signs and symptoms of dry eye after cataract surgery between subjects randomized to receive intraoperative dexamethasone in addition to the use of a standard topical post-op treatment regimen.

Forty patients requiring cataract surgery will be randomized to treatment of post-operative inflammation with a single intraoperative dexamethasone injection plus a standard course of topical ophthalmic corticosteroid drops or the standard treatment alone. Dry eye testing will be administered at baseline, 1 week and 3 weeks following surgery.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

Conditions

Dry Eye Syndromes

Interventions

dexamethasone intraocular suspension, 9%DRUG

single dose intracameral corticosteroid

Prednisolone Acetate 1% Oph SuspDRUG

topical ophthalmic steroid drop

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * undergoing bilateral cataract surgery Exclusion Criteria: * central corneal staining with fluorescein and/or a tear film osmolarity of greater than 340 in either eye

Locations (1)

Hauser Ross Surgical Center

Sycamore, Illinois, United States

Outcomes

Primary Outcomes

Evaluation of Intraoperative Use of Dexycu on Tear Film Osmolarity at 3 Weeks Postoperatively

Tear Film Osmolarity as measured on Tear Lab system; validated measure of Tear Film Osmolarity Osmolarity was reported in milliosmoles per liter (mOsmol/L)

Time frame: 3 weeks

Data from ClinicalTrials.gov

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