This pilot study will include up to 25 patients with cancer experiencing chemotherapy-induced peripheral neuropathy. Patients enrolled in the study will participate in a 10-week QiGong for Chemotherapy-Induced Neuropathy program. Patients will be evaluated before and after their program participation. Within 2 weeks before the program start date, patients will be administered an objective neuropathy assessment by a physician or nurse, and will complete questionnaires assessing chemotherapy-induced peripheral neuropathy, perceived cognitive functioning, quality of life, and cancer-related symptoms. Patients will repeat these assessments at the end of the last QiGong class and will be asked to provide feedback on the QiGong program as a whole. Self-report questionnaires will also be repeated one week after the last class. Total duration of subject participation will be 11-13 weeks. Total duration of the study is expected to be approximately 9 months.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
6
Guided Qi Gong class
Cedars Sinai Medical Center
Los Angeles, California, United States
Objective Modified Total Neuropathy Scale (mTNS) score
Change in the Modified Total Neuropathy Scale (mTNS) score from Baseline to T1 (last day of class)
Time frame: 10 weeks
Subjective Neurotoxicity Subscale score
Change in the Functional Assessment of Cancer Therapy/Gynecologic Oncology Group - Neurotoxicity (FACT/GOG-NTX) Subscale Score from Baseline to T1 (last day of class) and T2 (1-week follow-up).
Time frame: 11 weeks
Attendance
Number of QiGong classes attended by those who enroll
Time frame: 10 weeks
Retention
Completion of both pre- and post-assessments
Time frame: 10 weeks
Patient Interest
Percentage of patients approached who sign consent
Time frame: 1 week
Patient Evaluation of QiGong Program
Scores on the evaluation titled: QiGong Program Evaluation. Study participants will provide a score for 3 questions related to the QiGong intervention. The minimum value is 0 and maximum value is 4, and higher score means a better outcome. Participants will also be asked 4 additional questions about the class. The minimum value is 0 and the maximum value is 10, and higher score means a better outcome. A composite of all the scores for each participant will be calculated, with higher scores indicating a better outcome.
Time frame: 1 day
Perceived cognitive functioning
Change in the Functional Assessment of Cancer Therapy - Cognition (FACT-Cog) score from Baseline to T1 (last day of class) and T2 (1-week follow-up).
Time frame: 11 weeks
Physical Well-Being
Change in the FACT/GOG-NTX Physical Well-Being Subscale Score from Baseline to T1 (last day of class) and T2 (1-week follow-up).
Time frame: 11 weeks
Social/Family Well-Being
Change in the FACT/GOG-NTX Social/Family Well-Being Subscale Score from Baseline to T1 (last day of class) and T2 (1-week follow-up).
Time frame: 11 weeks
Emotional Well-Being
Change in the FACT/GOG-NTX Emotional Well-Being Subscale Score from Baseline to T1 (last day of class) and T2 (1-week follow-up).
Time frame: 11 weeks
Functional Well-Being
Change in the FACT/GOG-NTX Functional Well-Being Subscale Score from Baseline to T1 (last day of class) and T2 (1-week follow-up).
Time frame: 11 weeks
Impact on symptom experience
Change in the ESAS scores from Baseline to T1 (last day of class) and T2 (1-week follow-up).
Time frame: 11 weeks
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