This study aiming to investigate if difference in the timing of cumulus removal post retrieval would have any critical impact on fertilization and embryonic development.
Patients under 37 year old who were treated with controlled ovarian stimulation for ICSI were randomly divided into 2 groups; Group A: Oocytes were denudated immediately after oocyte retrieval , Group B: Oocytes were denudated 2 hours after retrieval and both groups were microinjected at 4 hours from ovum pickup. Microinjection was performed on all matured oocytes only and they were cultured to blastocyst stage.The rates of maturation, fertilization, good quality blastulation, chemical pregnancy and clinical pregnancy were analysed and compared between the two groups.
Study Type
OBSERVATIONAL
Enrollment
300
The time between ovum pickup and denudation of oocyte
Hawaa Fertility Center
Banhā, Qalyubia Governorate, Egypt
Day 5, good quality blastocyst
Assessment were done according to gardener classification
Time frame: 120 hour post ovum pickup
clinical pregnancy
Assessment was done by observation of a gestational sac at 6 wks
Time frame: 6 weeks from the last normal menstrual period
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