Use of Closed Loop Insulin Delivery for Glucose Control in Patients With Insulin Dependent Diabetes Mellitus After Kidney Transplantation

Inclusion Criteria: 1. Age ≥18.0 years old at time of consent 2. History of insulin requiring diabetes mellitus, type 1 or type 2, who have end stage renal disease (ESRD) 3. Expected to undergo deceased or living donor kidney transplant surgery 4. History of insulin prescription (past or current use) 5. If female and sexually active, must agree to use a form of contraception to prevent pregnancy while a participant in the study. A negative serum or urine pregnancy test will be required for all females of childbearing potential. Participants who become pregnant will be discontinued from the study. 6. Willingness to switch to lispro (Humalog) or aspart (Novolog) if not using already, and to use no other insulin besides lispro (Humalog) or aspart (Novolog) during the study 7. Total daily insulin dose (TDD) at least 10 U/day 8. An understanding and willingness to follow the protocol and signed informed consent Exclusion Criteria: 1. Pregnancy or intent to become pregnant during the trial 2. Currently breastfeeding or planning to breastfeed 3. A known medical condition that in the judgment of the investigator might interfere with the completion of the protocol. 4. Having a family member(s) employed by Tandem Diabetes Care, Inc. or having a direct supervisor at place of employment who is also directly involved in conducting the clinical trial (as a study investigator, coordinator, etc.); or having a first-degree relative who is directly involved in conducting the clinical trial. 5. Patients who have consented to participate in other interventional trials will be excluded or given the opportunity to exit from the study