The aim of the prospective study is to assess the feasibility of a screening and baseline measurement protocol that is planned for a main study (PRÄP-GO) in a collective of 30 patients ageing 70+ scheduled for elective surgery. Comprehensive geriatric assessment scores and modified Fried frailty phenotype component evaluation are performed in all patients at baseline before elective surgery. The assessment of cognitive tests is conducted with a battery of neuropsychological tests, computer-based tests from the Cambridge Neuropsychological Test Automated Battery \[CANTAB®\] and non-computer based tests. Frailty scores from 0 to 5 (i.e., 1 point for each component; 0 = best to 5 = worst) represent robust (0), pre-frail (1-2), and frail (3-5) health status. 10 patients without Frailty, 10 patients with Pre-Frailty and 10 patients with Frailty should be analyzed in this study and receive further comprehensive geriatric assessment testing up to seven days after surgery/discharge (before 7 postoperative days).
Study Type
OBSERVATIONAL
Enrollment
30
Department of Anesthesiology and Operative Intensive Care Medicine (CCM/CVK), Charité - Universitätsmedizin Berlin
Berlin, Germany
Duration to run the test battery
The duration of the screening test battery is measured with a stopwatch.
Time frame: 1 day (Once only at screening)
Acceptance of test battery
The study patient´s acceptance of the screening test battery is measured with a questionnaire.
Time frame: 1 day (Once only at screening)
Problems to conduct the test battery
Problems while performing the test battery are categorized according to a standardized protocol.
Time frame: 1 day (Once only at screening)
Change in pain
Pain is measured with a pain score, a higher score indicates more pain.
Time frame: Baseline, day 3 after surgery and discharge or day 7 after surgery
Intelligibility of the patient Diary 1
Number of completed items
Time frame: Up to day 7 after surgery
Intelligibility of the patient Diary 2
Number of completed days
Time frame: Up to day 7 after surgery
Intelligibility of the patient Diary 3
Coherence of the diary with clinical patient record
Time frame: Up to day 7 after surgery
Implementation rate of the patient Diary 3
Time frame: Up to day 7 after surgery
Handgrip strength
Handgrip strength measured using a Dynamometer.
Time frame: Baseline, day 3 after surgery and discharge or day 7 after surgery
Mobility
Mobility is measured using the Charité Mobilitäts-Index (CHARMI®).
Time frame: Baseline, day 3 after the operation and discharge or day 7 after surgery
Nutritional status 1
Nutritional status 1 is measured using serum albumin.
Time frame: Baseline and discharge or day 7 after surgery
Nutritional status 2
Nutritional status 2 is measured using arm circumference.
Time frame: Baseline and discharge or day 7 after surgery
Nutritional status 3
Nutritional status 3 is measured using calf circumference.
Time frame: Baseline and discharge or day 7 after surgery
Nutritional status 4
Nutritional status 4 is measured using the Mini Nutritional Assessment - Short Form (MNA®-SF).
Time frame: Baseline and discharge or day 7 after surgery
Intra- and postoperative organ complications
Time frame: Up to 7 days after surgery
Length of intensive care unit stay
Time frame: Participants will be followed for the duration of hospital stay, an expected average of 1 day.
Length of stay
Time frame: Participants will be followed for the duration of hospital stay, an expected average of 7 days.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.