Dual Arterial Phase Liver CT in Patients With Suspected Portal Hypertension

N/AUnknownNCT04195971

Seoul National University Hospital69 enrolled

Overview

Patients with liver cirrhosis is at risk of developing HCC. To diagnose or detect HCC at CT/MRI, optimal late arterial phase (LAP) acquisition is critical to capture the tumor. For LAP acquisition, bolus-tracking is often used at CT. In patients with portal hypertension, however, bolus-tracking occasionally capture early arterial phase which may be related with slow portomesenteric flow. In this study, we obtain dual arterial phase in patients with suspected portal hypertension and determine whether this protocol (dual arterial phase) would provide higher incidence of LAP acquisition than single arterial phase acquisition.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

HCC Cirrhosis, Liver

Interventions

Eligibility

Sex: ALLMin age: 20 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Older than 20 years * Liver cirrhosis diagnosed with characteristic imaging feature or histology * Presence of portal hypertension sign (splenomegaly and varices) * Scheduled for liver CT * And signed informed consent Exclusion Criteria: * Relative or absolute contra-indication of contrast-enhanced CT

Outcomes

Primary Outcomes

Incidence of optimal late arterial phase acquisition

incidences of optimal late arterial phase acquisition in 1st and 2nd acquisition of arterial phase in this protocol (dual arterial phase) CT.

Time frame: 1 months after study completion