Socioeconomic Status, Secondary Prevention Activities and Recurrence After a Myocardial Infarction

N/ACompletedNCT04199663

Karolinska Institutet30,191 enrolled

Overview

This is a nationwide cohort study on real-world patients (n≈30,000) surviving a first myocardial infarction (MI) 2006-2013 and alive to attend a routine 1-year follow-up. Associations between Socioeconomic Status (SES) and secondary preventive actions (SPAs) throughout the first year is studied and assessed as possible mechanisms underlying the increased risk of a first recurrent hard cardiocvascular (CV) outcome, recurrent atherosclerotic cardiovascular disease (rASCVD), in patients with low Socioeconomic Status during long-term follow-up (2006-2018).

Study Type

OBSERVATIONAL

Enrollment

30,191

Conditions

Socioeconomic Status Secondary Prevention Myocardial Infarction Cardiovascular Disease Stroke

Eligibility

Sex: ALLMin age: 18 YearsMax age: 76 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Swedish resident * Alive and registered in The Swedish Websystem for Enhancement and Development of Evidence based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART)'s secondary prevention subregistry between 1 January 2006 and 31 December 2013 at the 1-year-revisit Exclusion Criteria: * Age \>76 years at baseline * Missing data for disposable household income * History of MI, stroke, coronary artery bypass graft (CABG), or percutaneous coronary intervention (PCI) prior to the index MI * Not present in initial care registry (RiksHIA) * Date of index MI before 2004 or missing * revisit outside 13±2 month window post-MI

Outcomes

Primary Outcomes

first recurrent atherosclerotic cardiovascular disease event (rASCVD)

composite outcome including non-fatal MI (I210-I214, I219, I220, I221, I228 or I229) or coronary heart disease death (CHD) (I210-I214, I219, I220, I221, I228, I229, I461 or I469) or fatal or non-fatal ischemic stroke (I630-I635, I638 or I639) according to the International Classification of Diseases 10th edition (ICD-10)

Time frame: from date of 1-year visit post-MI (baseline) until date of outcome, censoring or study end (2018)